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Os bioestimuladores de colágeno são substâncias injetáveis totalmente absorvíveis pelo organismo, capazes de diminuir a flacidez facial e diminuir as rugas. Normalmente compostas por ácido polilático ou hidroxiapatita de cálcio, essas substâncias não apresentam reação alérgica, aumentam a espessura e rejuvenescem a pele.